New Publication from the Anderson Lab in Oncotarget
"Insight into the PTEN - p85α interaction and lipid binding properties of the p85α BH domain"
New Publication from the Vizeacoumar, Bonham and Wu Labs in Mol Oncol
Molecular characterization of an MLL1 fusion and its role in chromosomal instability
New Publication from Xiang Lab in Cell Mol Immunol
"TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis"
Dr. Franco Vizeacoumar joins the editorial board of Biochemistry and Cell Biology
This bimonthly journal explores every aspect of general biochemistry and provides updates on current research in cellular and molecular biology.
New Review Article Published by the Sharma Lab in Cell Calcium
Calmodulin-binding proteins: A journey of 40 years
Dr. Deborah Anderson was awarded a CoMRad Grant
Dr. Deborah Anderson was awarded a CoMRad grant from the College of Medicine for a project called: "Identification of new drugs to treat triple negative breast cancer".
Dr. Jim Xiang was awarded a CoMRad Grant
Dr. Jim Xiang was awarded a CoMRad grant from the College of Medicine for a project called: "Critical role of FAK/RhoA in regulation of mTORC1/PKM2 pathway controlling epithelial-mesenchymal transition of triple-negative breast cancer".
New Publication from the Vizeacoumar, Bonham and Wu Labs in NPJ Syst Biol Appl
Expression-based analyses indicate a central role for hypoxia in driving tumor plasticity through microenvironment remodeling and chromosomal instability
New Publication from Xiang Lab in Onco Targets Ther
"Novel EXO-T vaccine using polyclonal CD4+ T cells armed with HER2-specific exosomes for HER2-positive breast cancer"
New Review Article Published by the Xiang Lab in Onco Targets Ther
Novel EXO-T vaccine using polyclonal CD4+ T cells armed with HER2-specific exosomes for HER2-positive breast cancer
Hussain Elhasasna awarded College of Medicine Graduate Student Award (CoMGRAD)
Congratulations to Hussain Elhasasna (Vizeacoumar Lab).
New Publication from the Lukong and Vizeacoumar Labs in Proteome Sci
Global phosphoproteomic analysis identifies SRMS-regulated secondary signaling intermediates
Congratulations to Dr. Raghu Goel - new Ph.D. in Biochemistry
Raghu Goel (Lukong lab) passed his PhD defence on August 7, 2018. His thesis is titled: "Phosphoproteomics analyses to identify the candidate substrates and signaling intermediates of the non-receptor tyrosine kinase, SRMS".
New Publication from Xiang and Lukong Labs in Int J Mol Sci
"Simulated Microgravity Reduces Focal Adhesions and Alters Cytoskeleton and Nuclear Positioning Leading to Enhanced Apoptosis via Suppressing FAK/RhoA-Mediated mTORC1/NF-κB and ERK1/2 Pathways"
New Publication from Xiang Lab in Immunotargets
"Multiple effects of CD40-CD40L axis in immunity against infection and cancer"
Congratulations Poster Winners at the fifth Saskatchewan Cancer Research Conference
The fifth Saskatchewan Cancer Research Conference was held June 13, 2018 in Saskatoon, with 125 registered participants from a wide range of disciplines in attendance. This conference recognizes and promotes the excellent cancer research within the province and provides valuable learning and networking opportunities for the participants.
New Publication from Xiang Lab in Cell Mol Immunol
"Mannose-6-phosphate receptor: a novel regulator of T cell immunity"
New Publication from Anderson Lab in Sci Rep
"Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation"
Congratulations Riley Crittenden, on receiving Biomedical Summer Research Project Award
from the College of Medicine
New Publication from Lukong Lab in Mol Cell Proteomics
"Phosphoproteomics Analysis Identifies Novel Candidate Substrates of the Nonreceptor Tyrosine Kinase, Src-related Kinase Lacking C-terminal Regulatory Tyrosine and N-terminal Myristoylation Sites (SRMS)"
Congratulations Brooke Aspen, on receiving an NSERC USRA award
Brooke Aspen (Vizeacoumar Lab) was awarded an NSERC Undergraduate Summer Research Award to support her studies during the summer months in the Vizeacoumar Lab.
Dr. Aizhang Xu awarded a Saskatchewan Cancer Agency Postdoctoral Fellowship
Congratulations to Aizhang Xu (Xiang Lab), the recipient of a Saskatchewan Cancer Agency Postdoctoral Fellowship, a two-year award. Aizhang’s project is titled: “Beneficial cytotoxic T lymphocytes response derived from irreversible electroporation ablation of breast cancer”.
Dr. Archana Kumari awarded a Saskatchewan Cancer Agency Postdoctoral Fellowship
Congratulations to Archana Kumari (Vizeacoumar Lab), the recipient of a Saskatchewan Cancer Agency Postdoctoral Fellowship, a two-year award. Archana’s project is titled: “Exploring the landscape of circular RNA expression in breast cancer”.
Dr. Deborah Anderson awarded a Saskatchewan Cancer Agency Grant
Dr. Deborah Anderson was awarded a 2-year grant from the Saskatchewan Health Research Foundation. Title: ‘New targets for metastatic breast cancer.’
Dr. Jim Xiang awarded a Saskatchewan Cancer Agency Grant
Dr. Jim Xiang was awarded a 2-year grant from the Saskatchewan Cancer Agency. Title: ‘Therapeutic immunity of heterologous HER2-specific HuRt-Texo vaccination against trastuzumab-resistant breast cancer in BLT/NSG humanized mice.’
Dr. Franco Vizeacoumar awarded a Saskatchewan Cancer Agency Grant
Dr. Franco Vizeacoumar was awarded a 2-year grant from the Saskatchewan Cancer Agency. Title: ‘Characterization of the cell surface protein GPR112 as a potential cancer drug target.’
New Publication from Xiang Lab in Vaccine
"Heterologous human/rat HER2-specific exosome-targeted T cell vaccine stimulates potent humoral and CTL responses leading to enhanced circumvention of HER2 tolerance in double transgenic HLA-A2/HER2 mice"
New Publication from Xiang Lab in Sci Rep
"Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways"
New Publication from Lukong Lab in Chem Biol Interact
"Caffeine-supplemented diet modulates oxidative stress markers and improves locomotor behavior in the lobster cockroach Nauphoeta cinerea"
New Publication from Wu, Lukong and Vizeacoumar Labs in Biochem J
"Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding"